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Abstract
Gerontology & Geriatrics Studies
Chronic Obstructive Pulmonary Disease (COPD) and Sarcopenia: A Bidirectional Pathway
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Open or Close Daniela Patino Hernandez*
Geriatric Medicine Unit, Ageing Institute. Pontificia Universidad Javeriana. Bogotá, Colombia
*Corresponding author: Daniela Patino-Hernandez, Geriatric Medicine Unit, Institute of Aging, Pontifical Xavierian University, Carrera 7 No. 40-62 - Hospital Universitario San Ignacio, piso 8. Facultad de Medicina. City: Bogotá D.C. Country: Colombia
Submission: September 28, 2017; Published: November 09, 2017
ISSN: 2578-0093Volume1 Issue1
Abstract
Chronic diseases increase their prevalence as the population pyramid inverses [1], and respiratory diseases are among the most frequent conditions in elderly individuals [2]. For instance, chronic obstructive pulmonary disease (COPD) is a multi factorial entity with a wide range of clinical manifestations, and a leading cause of morbidity and mortality worldwide [3]. The pathophysiology of COPD is as wide as its clinical presentation. However, chronic inflammation is an essential component. Also, increased inflammation is associated with a higher rate of exacerbations and a faster decline in lung function [3], while systemic inflammation contributes to the extra-pulmonary manifestations of COPD.
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