Abstract

Atypical fibroxanthoma (AFX) is an uncommon skin neoplasm developed mainly in the head and neck region in older senior patients. Prolonged sun exposure, actinic damaged, history of previous neoplasms and immunosuppressant are considered the most important risks factors. Subcutaneous extension of these tumors is related to a more aggressive biology. Metastatic extension is extremely rare but might lead to a fatal outcome. Differential diagnosis might be a challenge for pathologist due to its uncharacteristic features. We report the case of an elder patient who presented a recurrent AFX and who developed lung and lymph node metastasis. Even though treatment with chemotherapy and radiation was proposed, the patient final passed away due to a worsening of his condition.

Keywords: Atypical fibroxanthoma; Metastases; Skin neoplasm