1Department of Otolaryngology-Head and Neck Surgery, CHP Hospital Santo António, Portugal
2Department of Microbiology, CHP Hospital Santo António, Portugal
3Faculty of Pharmacy, University of Coimbra, Portugal
4Abel Salazar Biomedical Sciences Institute, Portugal
5CUF Infante Santo Hospital, Portugal
*Corresponding author: José Gameirodos Santos, Department of Otolaryngology-Head and Neck Surgery, CHP-Hospital Santo António, Serviçode ORL–CHPP porto Largo Prof Abel Salazar 4099-001-Porto, Portugal
Submission: September 09, 2017;Published: October 27, 2017
ISSN: 2637-7780Volume1 Issue1
Introduction: The most common microbial agents in the etiology of chronic rhinosinusitis are defined in the literature as Staphylococcus aureus, Staphylococcus coagulase-negative and Streptococcus spp. In healthy individuals these same microorganisms are also the most frequent (mainly Staphylococcus coagulase negative) ascolonizing flora agents. We often encounter a poly microbial colonization of the nose and sinuses. The contribution of the different pathogens for the disease remains sun certain. The aim of this study is to compare the microbial flora found in patients with chronic rhinosinusitis with and without nasal polyps.
Methods: Prospective clinical study. 110 patients with indication for endonasal microsurgery by chronic rhinosinusitis were evaluated. Patients were divided into two groups: with nasalpolyps (70) and without nasalpolyps (40). During surgery, mucosa of the middle meat us/anterior ethmoid was collected, in the side with the highest score Lund-McKay and sent for bacteriological analysis.
Results: There was a predominance of aerobic Gram-positive bacteria, followed by aerobic Gram-negative and an aerobic bacteria. When evaluated separately the groups with and without nasalpolyps, there was a predominance, in both, of Gram-positive bacteria. However, in the group with nasalpolyps, these cond higher prevalence was of aerobic Gram-negative bacteria and only after an aerobic bacteria while in the group without nasalpolyps there was a predominance of an aerobic bacteria in relation to aerobic Gram-negative bacteria.
Conclusion: As recently suggested by several authors, nasalpolyps may not beast age of chronic rhinosinusitis but a distinct disease entity. The existence of distinct microbial flora eventually comes to corroborate this hypothesis.
Keywords: Chronic rhinosinusitis; Polyposis; Microbiology