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Developments in Clinical & Medical Pathology

Gestational Diabetes Mellitus: Pathophysiology and Risk Factors

  • Open or Close Sununta Youngwanichsetha*

    Department of Nursing, Prince of Songkla University, Thailand

    *Corresponding author: ISununta Youngwanichsetha, RN, PhD, Assistance Professor, Faculty of Nursing, Prince of Songkla University, 90112, Hat Yai,Songkhla, Thailand

Submission: April 14, 2018;Published: April 20, 2018

Volume1 Issue2
April 2018


Prevalence of gestational diabetes mellitus (GDM) is increasing among pregnant women worldwide. Understanding of GDM pathophysiology and risk factors is helpful to prevent its complications. Known risk factors of GDM are genetic and unhealthy behaviors. Genetic risk factor is associated with pancreatic beta cell dysfunction and impaired carbohydrate and fat metabolism. In addition, unhealthy behaviors including dietary pattern and lack of exercise are known to promote development of diabetes. Overeating of unhealthy diet causes obesity, insulin resistance, and endothelial cell dysfunction.

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