Method: This is a cross-sectional study designed to assess the awareness, analyze collaboration, perception and acceptance of healthcare professionals in providing medication therapy management service in fourteen (14) hospital facilities. A self-administered questionnaire was used to collect relevant data. The questionnaire was designed from the objective of study which is derived through intensive literature review and abducted from the Core Element of MTM service version 2.0. A stratified random sampling using senatorial district, in Delta state Nigeria, as strata was adopted to survey the sample population

Results: The total study sample was 227 medical practitioners, 106 (46.70%) female and 121(53.30%) male. Among them were 58(25.47%) physicians, 114(63.43%) nurses, 14(6.16%) laboratory scientist and 11 (4.84%) other health care professions. Fewer respondents have heard about MTM (42.3%); only 22.7% of them admitted that collaboration with pharmacists in providing MTM helped to improve overall patient care. Respondents’ response on acceptance that pharmacists are adequately trained to provide clinical services to patients showed that 56.8% of them disagreed.

Conclusion: The health care professionals had little knowledge of Medication therapy management service, and the acceptance of collaborative practice with pharmacist rendering medication therapy management service has not been adequate among other members of the health care team. The measure of collaborative practice with pharmacist rendering Medication Therapy Management services has not been effective within health care practitioners in Delta State.

Keywords: Medication therapy management; Collaboration; Perception, Acceptance