Abstract

After the first case has appeared in China, the disease, COVID-19, continues to spread an omnipresent threat to global health. The reliable, fast, and effective diagnosis methods are important to control the pandemic. Today, the real-time Reverse Transcriptase (RT-PCR) test is the main diagnostic practice as a gold standard method for accurate diagnosis of this disease. On the other side, serological assays are easy to be implemented for disease screening. However, the actual limitations of these methods are required skilled personnel and specialized infrastructure. Thus, in this direction, there is an urgency to be implanted an appropriate method for the diagnosis of COVID-19 disease. Nowadays, the Reverse Transcription Loop-Mediated Isothermal Amplification (RT-LAMP) technique is preferred because of the portable, easily implanted, and effective for diagnosis. In this assay, three main diagnosis methods (RTPCR, serological tests, and RT-LAMP) are evaluated s within the scope of the COVID-19 diagnosis.

Keywords:SARS-CoV-2; COVID-19 disease; COVID-19 diagnosis methods