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Research in Pediatrics & Neonatology

Stem Cell Culture System Simulating Continuous Fluctuating Pressure in vivo

  • Open or CloseMuhang Li1,2, Junning Cui1,2*, Ran Tang1,2,3 and Kai Li3

    1Center of Ultra-precision Optoelectronic Instrument Engineering, China

    2Key Lab of Ultra/precision Intelligent Instrumentation (Harbin Institute of Technology), China

    3School of Life Science and Technology, China

    *Corresponding author: Junning Cui, Center of Ultra-precision Optoelectronic Instrument Engineering, Key Lab of Ultra/ precision Intelligent Instrumentation (Harbin Institute of Technology), Ministry of Industry and Information Technology, China

Submission: November 16, 2021Published: November 30, 2021

ISSN : 2688-8394
Volume2 Issue5

DOI: 10.31031/ACSR.2020.02.000550


In order to improve the survival rate of stem cells in therapy after large-scale culture and transplantation into patients, a stem cell culture system simulating continuous fluctuating pressure in vivo was proposed in this paper. The system analogs the human pulse signals by regularly regulating the internal pressure. It provides blood pressure training for the large-scale culture of stem cells in vitro, which can improve the survival rate after stem cell transplantation, so as to elevate the success rate of cell therapy, and finally provide direction for the development of new culture instrument.

Keywords: Continuous fluctuating pressure; Pulse signals simulation; Stem cell culture technology

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