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Advances in Complementary & Alternative medicine

Cannabinoids: Pivotal Role in Sepsis

  • Open or ClosePreeti Singh*

    College of Veterinary Science and Animal Husbandry, India

    *Corresponding author: Preeti Singh, College of Veterinary Science and Animal Husbandary, DUVASU, Mathura, India

Submission: August 17, 2018; Published: January 18, 2019

DOI: 10.31031/ACAM.2019.03.000568

ISSN: 2637-7802
Volume3 Issue4


Sepsis is a multifactorial disease with uncontrolled systemic production of inflammatory mediators (‘cytokine storm’) leading to systemic inflammatory response syndrome (SIRS) following microbial infection. It is characterized by vascular hyporeactivity, decreased tissue perfusion, tachypnoea, hyperthermia, systemic hypotension, multiorgans failure despite of antibiotic therapy, adequate fluid resuscitation and administration of vasopressors. Infections caused by bacteria (Gram +ve or Gram -ve), fungi, virus, parasites etc. or pathological conditions like ischaemia, burn, abdominal surgery, pancreatitis, haemorrhage etc. favour the developement of niche for sepsis.

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