Archives of Blood Transfusion & Disorders

Cocaine and Platelets Activation: Is there a Link?

  • Open or Close Siniscalchi A1*, Sanguigni S2, AndreoneV3, De Sarro GB4 and Gallelli L4

    1Department of Neurology, Annunziata Hospital, Italy

    2Department of Neurology, Madonna del Soccorso Hospital, S Benedetto del Tronto, Italy

    3Stroke Unit, Cardarelli Hospital, Napoli, Italy

    4Department of Health Science, University Magna Graecia of Catanzaro, Clinical Pharmacology and Pharmacovigilance Unit, Mater Domini University Hospital, Italy

    *Corresponding author: Antonio Siniscalchi, MD, Department of Neurology, Annunziata Hospital,Via Felice Migliori, 187100-Cosenza, Italy

Submission: February 27, 2018; Published: March 27, 2018

DOI: 10.31031/ABTD.2018.01.000511

ISSN: 2578-0239
Volume1 Issue3


Increasing evidence supports the relationship between substance abuse and stroke [1-4], Cocaine induces both hemorrhagic and ischemic stroke and the stroke type significantly varied according to type of cocaine formulation as well as contaminants and between current and previous cocaine users [1]. In fact, crack-use is associated with both ischaemic and hemorrhagic strokes while cocaine hydrochloride-use with hemorrhagic strokes [1,2]. Multiple mechanisms may be involved in the genesis of ischemic stroke in cocaine users.

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