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Advancements in Bioequivalence & Bioavailability

Seroprevalence of anti-Toxoplasma gondii Antibodies Among Aborted Ladies Attended to Atbara Teaching Hospital, River Nile State

Submission: January 21, 2019 Published: February 04, 2019

DOI: 10.31031/ABB.2019.02.000538

ISSN : 2640-9275
Volume2 Issue3


This cross-sectional study was conducted in Atbara area-River Nile state throughout February to November 2017. The purpose of this study was to determine the sero-prevalence of Toxoplasmosis among aborted women. One hundred and fifty-two subjects with the age ranged between 25-49 years old of mean age was 38+10 were included. Blood samples were taken from all subjects. All samples were examined to detect Toxoplasma gondii antibodies by using Latex, ICT and ELISA techniques. The study showed that the overall sero-prevalence of Toxoplasma parasite by different techniques was as follows: 35.5% by ELISA technique, 33.6% by Latex agglutination technique and 22.4% by ICT technique.

The overall prevalence of antibodies increased gradually with age reaching 54.6% in the age group (41-49) year followed by 32.9% in age group (31-40) year, then 12.5% in age group (20-30) year. Assuming ELISA technique as the gold standard method, the sensitivity and specificity of the LATEX technique were 94% and 100%, and for ICT technique were 64% and 100% respectively. The study found that Toxoplasma antibodies are more prevalent in women in contact with cats than in women who do not contact with cats.

Keywords: Seroprevalence; Toxoplasma gondii; Abortion

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