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Advancements in Bioequivalence & Bioavailability

Allometry Scalling in Drug Development

  • Open or Close Murugesh Kandasamy*

    Department of Pharmaceutical Chemistry, International Medical University, Malaysia

    *Corresponding author: Murugesh Kandasamy, Lecturer, Department of Pharmaceutical Chemistry, International Medical University, No. 126 JalanJalil Perkasa 19, Bukit Jalil 57000 Kuala Lumpur, Malaysia

Submission: February 09, 2018; Published: June 07, 2018

DOI: 10.31031/ABB.2018.01.000512

ISSN 2640-9275
Volume1 Issue3


Allometry is about the study of body size and its outcomes, it is described as ‘by a different measure’, and in allometric system the proportions are changed in a regular fashion [1]. Allometry, which is the oldest of the approaches and still widely applied in biology, is concerned with the study of the relationship between the size and function of components of the body and growth or size of the whole body [2]. Alternatively, to study the species change in a specific factor which correlates with difference in size of the species. Allometry is centered on the prediction (an exact prediction) by considering the physiological, anatomical and biochemical parallels among animals, which can be explained by mathematical models. It is now an established fact that many physiological processes and size of the organ that exhibit a power-law relationship with the body weight of the species. This relationship is defined as the scientific source of allometric scaling [3,4].

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