Abstract

Multiple Myeloma (MM) is generally located in the Bone Marrow (BM) and associated with a wide spectrum of clinical, laboratory, and radiological findings [1]. Conversely, Solitary Plasmacytoma (SP) is characterized by a single mass of clonal plasma cells, with no or minimal BM plasmacytosis and with no other symptoms than those derived from the primary lesion [2]. The cases with spine involvement and spine cord suffering from compression always were very complicated and challenging.

Methods: We describe two cases of SP and MM with severe spine cord compression treated surgically with indication to address the compression and stabilization of the affected segments with subsequent treatment in hematology and oncology.
Results: In both cases the surgery was a success, the patient with SP survived 3 years and one month and the patient with MM-1 year and 3 months.
Conclusion: Outcomes of surgical interventions for these patients with spine cord compression and spinal instability due to multiple myeloma and plasmacytoma of the spine was with improved neurological function following surgery and no instrumentation failure.

Keywords:Plasmacytoma; Myeloma; Spine

Abbreviations:MM-Multiple Myeloma; BM-Bone Marrow; SP-Solitary Plasmacytoma; SEP-Solitary Extramedullary Plasmacytoma; IMWG-International Myeloma Working Group