1Laboratory of Genetics, Department of Dance and Fitness, Poznań University of Physical Education, Poznań, Poland
2Department of General and Endocrine Surgery and Gastroenterological Oncology, Poznań University of Medical Sciences, Poznań, Poland
3Department of Gymnastics, Poznań University of Physical Education, Poznań, Poland
4Department of Health Sciences, Olsztyn University College, Olsztyn, Poland
5Faculty of Health and Life Sciences, Coventry University, Coventry, CV1 5FB, United Kingdom 6Department of Pedagogy, Poznań University of Physical Education, Poznań, Poland
*Corresponding author:mgr Jan Adamczyk, Department of Gymnastics, Poznań University of Physical Education, Poland
Submission: December 05, 2019;Published: April 16, 2020
ISSN: 2577-1914 Volume6 Issue2
The serum angiotensin converting enzyme (ACE) level in individuals with a DD genotype is two-fold
higher than those with an II genotype. The DD genotype is correlated with a higher risk of cardiovascular
diseases, lower adaptability to hypoxic conditions, as well as lower cardio-respiratory capacity. The aim
of the study was to examine the role of I/D polymorphisms in the ACE gene in surgical patients vs. healthy,
active individuals. Two groups were investigated in the study: 91 surgical patients and 39 physically active
controls. The level of adaptation to physical stress, compensating processes, and sense of well-being of
participants were determined with subjective and objective inferential methods. Additionally, the represented
ACE gene polymorphism was evaluated using molecular analyses.
The role of the DD vs. II genotype is unclear in healthy, active individuals. Whilst in patients who regularly
participated in sport accrued shorter hospital stay time (P = 0.04). The type of surgery performed
significantly affects patients’ time to convalescence (P = 0.03). Patients’ time in hospital after oncological
surgeries is longer, regardless of whether chemotherapy was received or not. Based on the collected data,
it was not possible to indicate a common genotype predisposing resistance to physical stress in both
examined groups, with no statistically significant correlation between the ID polymorphism of ACE gene
in either group. However, the noted tendencies may suggest a role of allele I and II genotypes in patient
convalescence and as such, necessitates further investigation.
Keywords: Genotype; Maximal intensity effort; Climbers; Surgical patients