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Abstract
Open Journal of Cardiology & Heart Diseases
Metabolomics in Cardiology: Is There a Role for Precision Medicine?
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Open or Close Gustavo Monnerat*
Institute of Biophysics Carlos Chagas Filho, Federal Universityof Rio de Janeiro, Brazil
*Corresponding author: Gustavo Monnerat, Institute of Biophysics Carlos Chagas Filho, Federal Universityof Rio de Janeiro, Rio de Janeiro, IBCCFUFRJ, Av. Carlos Chagas Filho 373 -CCS -Bloco G, Rio de Janeiro 21941-902, Brazil
Submission: February 20, 2018; Published: March 09, 2018
ISSN: 2578-0204Volume1 Issue4
Abstract
Heart diseases are the leading causes of death worldwide. In this regard, metabolic complications such as diabetes and obesity, promote systemic alterations, mainly characterized by the availability of energetic substrates, such glucose and lipid levels, and amino acids concentrations. In addition to the presence of ketone bodies, and an abnormal hormonal levels, mainly androgen mediators, growth factors as well as changes in insulin homeostasis. These general metabolic alterations promote disturbances in cardiomyocytes energetic metabolism, increasing the risk of cardiovascular complications.
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