Abstract

Ofloxacin is a synthetic fluoroquinolone broad-spectrum antibiotic used for the treatment of both Gram-positive and gram-negative bacterial infections. In this study, the impact of consciousness energy healing treatment (the Trivedi Effect®) on the physicochemical and thermal properties of ofloxacin powder sample was evaluated using modern analytical techniques. The ofloxacin was divided into control and the Biofield Energy Treated sample. Only the treated ofloxacin was received the Consciousness Energy Healing Treatment remotely by a well-known Biofield Energy Healer, Dahryn Trivedi. The particle size values in the treated ofloxacin powder were significantly increased by 10.96%(d10), 29.09%(d50), 14.03%(d90), and 12.48% {D(4,3)}; thus, the surface area was significantly decreased by 8.06% compared to the control ofloxacin. The PXRD peak intensities and crystallite sizes of the treated ofloxacin were significantly altered ranging from -70.76% to 4.73% and -70.36% to 314.81%, respectively; however, the average crystallite was significantly increased by 25.22% compared with the control sample. The latent heat of fusion and decomposition was significantly altered by 13.43% and -53%, respectively in the treated ofloxacin compared with the control sample. The total weight loss was significantly decreased by 4.19%; however, the residue amount was significantly increased by 26.97% in the treated ofloxacin compared with the control sample. Thus, the Consciousness Energy Healing Treatment (the Trivedi Effect®) might lead to generate a new polymorphic form of ofloxacin with better shape, appearance, flowability, and thermally more stable compared to the control sample. The Consciousness Energy Healing Treated ofloxacin would be very useful to design novel pharmaceutical formulations for the better therapeutic response against urinary tract infections, infections of the urethra, and cervix, pneumonia, cellulitis, diarrhoea, bronchitis, plague, tuberculosis, prostatitis, and otitis media, etc.

Keywords: Complementary and alternative medicine; Ofloxacin; The Trivedi Effect®; Consciousness energy healing treatment; Particle size; PXRD; DSC; TGA/DTG