1Smart Bio-Interfaces, Italy
2 Department of Mechanical and Aerospace Engineering, Italy
*Corresponding author:Carlotta Pucci, Smart Bio-Interfaces, Italy
Submission: June 10, 2019; Published: September 13, 2019
ISSN: 2578-0336Volume1 Issue4
Despite the successful progresses in organ transplant, the organs shortage and the long waiting lists make it of the most challenging issues of our times. In fact, just a small percentage of patients receive transplants [1,2]. while every day around 18 people die waiting for them . The possibility to create de novo tissues and organs and/or to promote their regeneration is of prominent interest in the research community. In the last years, many innovative approaches have been introduced and new technological advancements are undergoing. Currently, the most diffused methodologies rely on regenerative medicine, that combines the use of stem cells, stimulated with specific factors, and scaffolds, where cells can grow to substitute damaged tissues, inducing their repair and improving their functions . Scaffolds possess a defined structure, with precise pore size and distribution [5,6], and determined mechanical properties which can tackle stress ensuring biological interconnections .