Abstract

In human body, skin is the largest and one of the most complex organs. It is one of the main components of our innate immune system. Being the outer most part of human body, skin is vulnerable to different harmful external factors, especially fire [1]. In case of burn injury there is severe skin damage causing alteration of dermal cells, biomolecule homeostasis and tissue architecture. Since, the dermis layer of skin is severely damaged, dermal reconstruction is the critical procedure in wound healing. Burnt wound is frequently associated with trauma [2]. Again, continuous production of fluid and persistence of pathogen makes the healing process worse. Thus, there are many clinical challenges associated with the treatment of burn injured patients suffering from acute or chronic wounds.