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Abstract

Cohesive Journal of Microbiology & Infectious Disease

Synthetic Peptide Antigens and Common Usage Areas

  • Open or CloseGülnur Tarhan*

    Department of Medical Microbiology, Turkey

    *Corresponding author:Gülnur Tarhan, Department of Medical Microbiology, Turkey

Submission: September 27, 2019; Published: October 16, 2019

DOI: 10.31031/CJMI.2019.03.000558

ISSN: 2578-0190
Volume3 Issue2

Abstract

Synthetic peptide antigens; molecular biology, genetics, biochemistry, microbiology, etc. in the field of antibiotic drug development, antibody production and vaccine development has been the subject of numerous research studies. These antigens are widely used in the industry for the diagnosis, treatment and prevention of genetic and metabolic diseases, especially infectious diseases. This technology is mainly based on the selection of epitopes found in natural structures and causing strong immune response, synthesis of amino acid sequences by various methods, coupling with the carrier molecule and delivery to the organism with the appropriate adjuvant. The most important advantage is that these molecules can be synthesized in the desired amount and in pure form. In various studies, vaccines prepared in this way received various levels of immune response. However, due to the absence of secondary and tertiary structures of the synthesized molecules, the immune response was low.

Keywords:Synthetic peptide antigens; Usage area; Vaccine

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