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Abstract

Significances of Bioengineering & Biosciences

Noncoding RNA Modulation for Cardiovascular Therapeutics
  • Open or Close Seahyoung Lee, Hyang-Hee Seo, and Ki-Chul Hwang*

    1Institute for Bio-Medical Convergence, College of Medicine, Catholic Kwandong University, Korea

    *Corresponding author: Ki-Chul Hwang, Institute for Bio-Medical Convergence, College of Medicine, Catholic Kwandong University, Gangneung, Korea, Email: kchwang@cku.ac.kr

Submission: March 15, 2018;Published: April 03, 2018

Volume1 Issue3
April 2018

Abstract

Cardiovascular diseasesare multifactorial diseases that involve alteration of multiple genes and subsequent phenotypic changes. Non-coding RNAs regulate gene expression, affecting many physiological and pathophysiological processes in humans. Accumulating evidence indicates that noncoding RNA, such as microRNAs, expression profile changes can lead to cardiovascular diseases. This article reviews the current findings regarding the roles of noncoding RNAs in cardiovascular diseases, and strategy to modulate them for therapeutics.

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