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1Department of Biological Science, Santa Cruz State University, Brazil
2Department of Physiological Sciences, Federal University of Espirito Santo, Brazil
*Corresponding author: Valério Garrone Barauna, Department of Physiological Sciences, Laboratory of Molecular and Cellular Physiology, Health Sciences Center, Federal University of Espírito Santo, Av. Marechal Campos, 1468 -Maruípe-Espírito Santo-Vitória, 29043900, Brazil
Submission: March 09, 2018; Published: June 19, 2018
ISSN: 2578-0204Volume2 Issue2
Coronary artery bypass graft surgery is the most frequently performed surgical intervention for relieving consequences associated with myocardial infarction. Despite its efficiency and advances in the methodology of collection, preservation and early onset antithrombotic treatment, vein graft failure is estimated between 15 and 30% during the first year. After 10 years of surgery, only 50% of these grafts are free of significant stenosis. Thrombosis, intimalhyperplasia, and accelerated atherosclerosis are the primary events pathophysiological of vein graft [1,2]. Successful vein graft adaptation is a complex process. In the vein graft procedure, a vein segment is submitted to arterial haemodynamic condition and thus genes associated with venous and arterial identities can be modulated as triggers to the adaptive response. Biomechanical factors, such as shear stress and stretch, are responsible for disturbed flow patterns which make the vein susceptible to remodeling within timal thickening which reduces grafts patency [3].
Ph.D in Agriculture from Faculty of Agriculture, Tohoku University
Research Professor, PhD, Holistic Research Institute
Professor, Chief Doctor, Director of Department of Pediatric Surgery, Associate Director of Department of Surgery, Doctoral Supervisor Tongji hospital, Tongji medical college, Huazhong University of Science and Technology
Senior Research Engineer and Professor, Center for Refining and Petrochemicals, Research Institute, King Fahd University of Petroleum and Minerals (KFUPM), Dhahran, Saudi Arabia
Fellow of International Agency for Standards and Ratings (IASR), Edith Cowan University, Sarich Neuroscience Research Institute
Chancellor Emeritus / Professor Emeritus of Chemistry and Physics, University of Missouri–St. Louis
Ph.D in Science from the Federal University of Alagoas, UFAL, Brazil
Assistant Professor in College of Architecture, Art and Design
Interim Dean, College of Education and Health Sciences, Director of Biomechanics Laboratory, Sport Science Innovation Program, Bridgewater State University
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