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Abstract

Open Journal of Cardiology & Heart Diseases

Recent Progress in the Association of TPM1 in Cardiogenesis, Myofibrillogenesis, and Heart Diseases

Submission: February 02, 2018; Published: February 21, 2018

DOI: 10.31031/OJCHD.2018.01.000511

ISSN: 2578-0204
Volume1 Issue3

Abstract

Tropomyosins, a family of actin-binding, coiled-coil dimeric proteins, are found in all eukaryotic organisms from yeast to man. Tropomyosin (TPM) is best known for its role in muscle contraction. It is a component of thin filaments in muscle cells and also a component of microfilaments in non-muscle cells The protein was discovered in the 1940s as a component of the actin filaments of striated muscle [1].

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