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Abstract

Novel Approaches in Cancer Study

Immune Checkpoint Inhibitors in Triple Negative Breast Cancer

  • Open or Close Nibash Budhathoki1, Ajay Dhakal2* and Mateusz Opyrchal2

    1Department of Medicine, Interfaith Medical Center, USA

    2Department of Medicine, Roswell Park Cancer Institute, USA

    *Corresponding author: Ajay Dhakal, Clinical Fellow, Department of Medicine, Roswell Park Cancer Institute, University at Buffalo, Elm and Carlton Streets, 14263, Buffalo, New York, USA

Submission: August 09, 2017; Published: August 21, 2017

DOI: 10.31031/NACS.2017.01.000501

ISSN:2637-773X
Volume1 Issue1

Abstract

Keywords:Immune Checkpoint Inhibitors; Triple Negative Breast Cancer; Breast Cancer; PD1; PD-L1, Pembrolizumab; Nivolumab; Atezolizumab

Abbreviations: CTLA4: Cytotoxic T Lymphocyte Antigen 4; PD1: Programmed Death 1; BMS: Bristol Myers Squibb; TIL: Tumor Infiltrating Lymphocytes; TNBC: Triple Negative Breast Cancer; IHC: Immunohistochemistry; CR: Complete Response; PR: Partial Response; SD: Stable Disease; PFS: Progression Free Survival; IC: Immune Cells; ORR: Overall Response Rate; pCR: Pathological Complete Response; HR: Hormone Receptor

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