Abstract

Present review article determine the analytical methods for the quantitative determinations of Enalapril (ACE Inhibitor) by one of the spectroscopic technique (UV spectrophotometry) and separation technique such as High-Performance Liquid chromatography (HPLC).Pharmaceuticals dosage formulations and human serum is needed for effective analytical procedure and quality control of Enalapril in clinical and pharmaceutical practices. An extensive survey of the literature published in various pharmaceutical and analytical chemistry related journals has been compiled in its review. A synopsis of reported spectrophotometer and high-performance liquid chromatographic methods for Enalapril is integrated. This appraisal illustrate that majority of the HPLC methods reviewed are based on the quantitative analysis of drug in API (active Pharmaceutical ingredients) biological fluids and they are appropriate for therapeutic drug monitoring purpose.

Keywords: HPLC; UV spectrophotometer; Quality control analysis; Method development; Validation