Abstract

Stent procedure and balloon angioplasty are two major approaches used in the treatment of Cardio vascular diseases. There have been significant advances in the treatment of these disorders and complication resulting from these treatment options i.e. Restenosis. This article focuses on the evolution and the recent advances in the different treatment options available for the preventing Restenosis after vascular intervention. The focal point of this review is the approaches for a localized drug delivery in the vascular walls.

Keywords: Restenosis; Drug Delivery; Drug Eluting Stent; Drug Coated Balloon; Micro porous catheter

Abbreviations: LLL: Late lumen loss; BMS: Bare metal stent; DES: Drug Eluting stent; PAT: Paclitaxel; CVD: Cardio Vascular Diseases; NIH: Neo intimal Hyperplasia; TVR: Target Vessel Revascularization; SMC: Smooth Muscle Cell