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Abstract
Modern Approaches in Drug Designing
Inflammation and Breast Cancer
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Open or Close Li Pin Kao1,2*
1Department of Basic Medical Sciences, Purdue University, USA
2Centre for Cancer Research, Purdue University, USA
*Corresponding author: Li Pin Kao, Department of Basic Medical Sciences, Centre for Cancer Research, Purdue University, West Lafayette, USA
Submission: February 23, 2018; Published: May 24, 2018
ISSN: 2576-9170Volume2 Issue1
Abstract
Chronic inflammation is a critical factor in tumor progression. Adipocyte accumulation and cytokines storm during inflammation have a significant impact on breast cancer. The development of cancer arises from sites of infection, chronic irritation and inflammation. Furthermore, tumor seed in tumor microenvironment as seed and soil, orchestrated by inflammatory cells, is an indispensable for cells transformed into benign or malignancy status and further fostering proliferation, survival, and migration. These insights are fostering new anti-inflammatory therapeutic approaches to cancer development.
Keywords: Breast Cancer; Inflammation; Obesity
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