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Abstract

Modern Approaches in Drug Designing

Inflammation and Breast Cancer

  • Open or Close Li Pin Kao1,2*

    1Department of Basic Medical Sciences, Purdue University, USA

    2Centre for Cancer Research, Purdue University, USA

    *Corresponding author: Li Pin Kao, Department of Basic Medical Sciences, Centre for Cancer Research, Purdue University, West Lafayette, USA, Email: kaolipin@gmail.com

Submission: February 23, 2018; Published: May 24, 2018

DOI: 10.31031/MADD.2018.02.000528

ISSN: 2576-9170
Volume2 Issue1

Abstract

Chronic inflammation is a critical factor in tumor progression. Adipocyte accumulation and cytokines storm during inflammation have a significant impact on breast cancer. The development of cancer arises from sites of infection, chronic irritation and inflammation. Furthermore, tumor seed in tumor microenvironment as seed and soil, orchestrated by inflammatory cells, is an indispensable for cells transformed into benign or malignancy status and further fostering proliferation, survival, and migration. These insights are fostering new anti-inflammatory therapeutic approaches to cancer development.

Keywords: Breast Cancer; Inflammation; Obesity

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