Abstract

From biomedical literature “autism disorder are involved in young patient, that we have abnormalities (Imaging, histology) in some brain areas, and a compiles symptomatology. Genetic and environment can produce some unbalances in brain grow and immunitary situation is involved. Apoptotic signal contribute in brain growth and immunologic shock can unbalance the environment producing abnormalities.” We can see that some pharmacological molecules are been introduced in therapy in some brain pathologies with a specific mechanism: modulating the immune systems. We can see that some systemic immune modifications can umbalance this systems producing pharmacological effect in local place (as Brain). We can observe this phenomenon like a kind of toxicity that can be deeply investigated to discover new Pharmacological strategies. Aim of this work is to observe this kind of pathologies under a specific immune-toxicological aspect. We think that in this field are needed deeply new approaches in order to adeguately focus this kind of disorder. A different way to set this kind of pathologies can help in searching new pharmacological strategies.

Keywords: Toxicology; Brain pathology; Immune status; New pharmacological strategies