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Abstract

Modern Approaches in Drug Designing

Formulation and In-vitro Evaluation of Mouth Dissolving Tablets of Mirtazapine

Submission: October 13, 2017; Published: December 19, 2017

DOI: 10.31031/MADD.2017.01.000515

ISSN: 2576-9170
Volume1 Issue3

Abstract

In our present study we want to develop mouth dissolving tablets of mirtazapine. Mirtazapine, vivasol, explotab, camphor, magnesium stearate, talc, microcrystalline cellulose were used for the preparation of the tablets. The tablets were prepared by direct compression method and bulk density, tapped density, angle of repose, carr’s index, hausners ratio, weight variation, thickness, hardness, friability and in vitro drug release were evaluated. Formulation F6 was considered as optimized formulations for mouth dissolving tablet of mirtazapine.

Keywords: Mirtazapine; Vivasol; Explotab; Camphor; Mouth dissolving tablets

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