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Abstract

Modern Approaches in Drug Designing

INanomedicines, Should We Be Distinguishing…..?

  • Open or Close Nawal khalafallah*

    Department of Pharmaceutics, Egypt

    *Corresponding author: Nawal khalafallah, Department of Pharmaceutics, Faculty of Pharmacy, Alexandria University, Alexandria, Egypt

Submission: October 11, 2017; Published: November 09, 2017

DOI: 10.31031/MADD.2017.01.000508

ISSN: 2576-9170
Volume1 Issue2

Abstract

With the increase in nano-medicines reaching market approval, two formulation strategies are evident. In one approach, the drug itself is presented as nano-size particles prepared either by high shear homogenization of larger particles or by building up drug molecules into nano-sized entities. In the second approach, the drug is loaded into a nano-sized carrier (lipid or polymer, biodegradable or not, vesicular, particulate or capsular).In both approaches, system stabilization against aggregation is necessary to maintain shelf life stability if the formulation is presented in a liquid form. When identifying the anticipated improved therapy outcomes of nano-medicines, it is probably prudent to distinguish between the two formulation approaches.

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