1 Tuberculosis and Lung Disease Research Center, Tabriz University of Medical Sciences, Tabriz , Iran
2 Department of cardiology, School of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran
3 Department of Nursing, Ayatollah Mousavi Hospital, Zanjan University of Medical Sciences, Zanjan, Iran
*Corresponding author:Khalil Mahmoodi, Associate Professor, Department of Internal Medicine, School of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran, Tel: 09122410801; Email: firstname.lastname@example.org
Submission: February 22, 2018; Published: March 22, 2018
ISSN: 2577-2007Volume2 Issue1
Various risk factors including blood iron may create coronary artery diseases and lead to myocardial infarction. There are controversies with regard to the impact of blood iron on myocardial infarction. Therefore, the aim of this paper was to investigate the relationship between iron reserves and the intensity of coronary artery stenos is among angiographic candidates in Zanjan, Iran. This was a cross sectional study. Samples were consisted of patients who were hospitalized for diagnostic coronary angiography in hospitals in an urban area of Iran. A convenient sampling method was used to recruit samples via interviews and laboratory examinations for FBS, iron, TIBC, ferritin, creatinine serum, CBC, cholesterol, HDL and LDL. The samples were divided into control and intervention groups. After coronary angiography, the intervention group was evaluated by four different methods including the extent score, stenos is score, vessel score and Duke CAN Index. The samples were consisted of 89 men (60.1%) and 59 women (39.9%). The levels of ferritin (p=0.003) and iron (p=0.002), and transferrin saturation percent (p=0.002) showed significant differences between males and females (p=0.004).
The linear relationship between ferritin and the intensity of coronary artery stenosis was obtained by the first method (p=0.006), second method (p=0.002), third method (p=0.001) and forth method (p=0.003). No statistically significant relationships were reported between the transferrin saturation percent and the intensity of stenosis by the above-mentioned methods (p=0.32, p=0.89, p=0.77 and p=0.79). This study showed that the intensity of coronary artery stenosis had a relationship with the body iron reserves. This relationship only was available for ferritin and not for relationships between iron and the transferrin saturation percent. Therefore, ferritin could be a more reliable index for predicting the intensity of coronary artery stenosis.
Keywords: iron reserves, coronary artery, angiography, ferritin serum, Iran