Abstract

Scientists in developed countries have still discuss the situation of milk A1 and A2. The controversy is that one group of scientists claim of A1 type a cause of many health problems in human whereas other groups report beneficial effects of A1 type and declare both types of milk safe for children and adults. The biological function of milk is to supply nutrition and immunological protection to the young mammal. Milk should be consumed for adequate and balanced nutrition. Economically the important milk constituents include: fat, protein, Solid Not Fat (SNF), lactose and ash. More than 95% of the cow milk proteins are constituted by caseins and whey proteins. Among the caseins, beta-casein is the second most abundant protein and has excellent nutritional balance of amino acids. The composition of beta-casein of milk and milk products has become an important economic trait of dairy animal. Beta-CasoMorphin-7 (BCM7) is suggested to be a risk factor for human health bas it can potentially affect numerous opioid receptors in the nervous, endocrine and immune system. The aim of this review was to evaluate discussions of effect A1 and A2 milk Beta-casein gene on health.

Keywords: Beta-casein A1; Beta-casein A2; BCM-7; Cow milk

Abbreviations: BCM-7: Beta-CasoMorphin-7; CSN2: Beta-Casein; ASD: Autistic Spectral Disorder; SIDS: Sudden Infant Death Syndrome